{"id":14731,"date":"2012-12-04T16:30:31","date_gmt":"2012-12-04T15:30:31","guid":{"rendered":"https:\/\/ocasapiens-dweb.blogautore.repubblica.it\/?p=14731"},"modified":"2021-09-21T23:38:45","modified_gmt":"2021-09-21T21:38:45","slug":"alcolismo","status":"publish","type":"post","link":"https:\/\/archivio.ocasapiens.org\/index.php\/2012\/12\/04\/alcolismo\/","title":{"rendered":"Alcolismo"},"content":{"rendered":"<p><img decoding=\"async\" src=\"http:\/\/media.economist.com\/sites\/default\/files\/imagecache\/full-width\/images\/2012\/12\/blogs\/graphic-detail\/20121208_woc580.png\" alt=\"\" \/><\/p>\n<p><span style=\"font-size: 13px; line-height: 19px;\">Dall&#8217;<\/span><em>Economist<\/em><span style=\"font-size: 13px; line-height: 19px;\">, &#8220;<\/span><a href=\"\/\/www.economist.com\/blogs\/graphicdetail\/2012\/12\/daily-chart\" target=\"_blank\" rel=\"noopener\"><strong>Text Messaging Turns Twenty<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">&#8220;. Rif. anche il &#8220;<\/span><a href=\"http:\/\/www.economist.com\/blogs\/graphicdetail\/2012\/12\/christmas-countdown\" target=\"_blank\" rel=\"noopener\"><strong>Calendario dell&#8217;Avvento<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">&#8221; con i grafici pi\u00f9 significativi dell&#8217;anno.<\/span><\/p>\n<p><span style=\"font-size: 13px; line-height: 19px;\">Per le trattative di Doha, il <\/span><em><a href=\"http:\/\/www.guardian.co.uk\/environment\/blog\/2012\/dec\/03\/doha-climate-talks-co2-methane\" target=\"_self\" rel=\"noopener\">Guardian<\/a><\/em><span style=\"font-size: 13px; line-height: 19px;\"> mi sembra una buona fonte. La sorpresa ieri \u00e8 stata la manifestazione dell&#8217;<\/span><a href=\"https:\/\/www.facebook.com\/media\/set\/?set=a.276483192464134.57507.275042005941586&amp;type=3\" target=\"_blank\" rel=\"noopener\"><strong>Arab Youth Climate Movement<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">. <\/span><\/p>\n<p><span style=\"font-size: 13px; line-height: 19px;\">Per italofoni, Antonio Zecca e Luca Chiari hanno scritto per <\/span><a href=\"http:\/\/www.climalteranti.it\/2012\/12\/03\/esaurimento-dei-combustibili-fossili-riscaldamento-globale-e-innalzamento-del-livello-del-mare\/#comments\" target=\"_blank\" rel=\"noopener\"><strong>Climalteranti<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> una versione user friendly del loro <\/span><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0921818112001579\" target=\"_blank\" rel=\"noopener\"><strong>paper<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> su Global &amp; Planetary Change.<\/span><\/p>\n<p><span style=\"font-size: 13px; line-height: 19px;\">Per l&#8217;assemblea annua <\/span><a href=\"http:\/\/www.agu.org\/meetings\/fm09\/lectures\/lecture_videos\/A23A.shtml\" target=\"_blank\" rel=\"noopener\"><strong>dell&#8217;AGU<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> a San Francisco-\u00a0starring &#8220;<\/span><a href=\"https:\/\/twitter.com\/MichaelEMann\" target=\"_blank\" rel=\"noopener\"><strong>Mike<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">&#8221; in innumerevoli <\/span><a href=\"http:\/\/www.realclimate.org\/index.php\/archives\/2012\/12\/agu-time-again\/\" target=\"_blank\" rel=\"noopener\"><strong>sessioni<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">, mi sa che s&#8217;\u00e8 clonato &#8211; <\/span><a href=\"http:\/\/www.skepticalscience.com\/The_Greenhouse_Gas_Effect_All-Star_Fan_Club.html\" target=\"_blank\" rel=\"noopener\"><strong>Skeptical Science<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> elenca i membri del &#8220;Greenhouse Gas Effect All Star Fans Club&#8221;: Christopher Monckton; Roy Spencer; \u00a0Dick Lindzen, Roger Pielke Sr, Fred Singer, Jo Nova, David Evans, John Christy, William Kininmonth; Richard Tol, Judith Curry, Pat Michaels e&#8230;? No! S\u00ec, Anthony Watts.<\/span><br \/>\n<span style=\"font-size: 13px; line-height: 19px;\">Meno male che Donna Laframboise e la famigliola Idso continuano a sostenere che la CO2 non ha effetto serra o a Climate Monitor restavano senza guru&#8230;<\/span><\/p>\n<p>Complimenti a <a href=\"http:\/\/www.commonwealthclub.org\/events\/2012-12-04\/james-hansen-stephen-schneider-award\" target=\"_blank\" rel=\"noopener\">Jim avanzo di galera<\/a> per il premio Stephen Schneider; come il cappello gli sta proprio bene, la barba invece&#8230;<br \/>\n*<br \/>\nDal nuovo <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0959378012001215\" target=\"_blank\" rel=\"noopener\"><strong>paper<\/strong><\/a> di Naomi Oreskes et al:<\/p>\n<blockquote><p><em>Over the past two decades, skeptics of the reality and significance of anthropogenic climate change have frequently accused climate scientists of \u201calarmism\u201d&#8230; However&#8230; scientists have in fact been conservative in their projections of the impacts of climate change\u2026 \u00a0We suggest, therefore, that <strong>scientists are biased not toward alarmism but rather the reverse<\/strong>: toward cautious estimates&#8230; We call this tendency \u201cerring on the side of least drama (ESLD).<\/em><\/p><\/blockquote>\n<p><span style=\"font-weight: bold; font-size: 13px; line-height: 19px;\">La moscerina e noi<\/span><br \/>\nI <em>PNAS<\/em> anticipano il paper &#8211; ma no, non <a href=\"http:\/\/www.pnas.org\/site\/highlights\/highlights.xhtml#flies\" target=\"_blank\" rel=\"noopener\"><strong>questo<\/strong><\/a>! &#8211;\u00a0 &#8220;Acute ethanol responses in <em>Drosophila<\/em> are sexually dismorphic&#8221;:<\/p>\n<blockquote><p><em>Sex differences in acute ethanol responses, which occur in humans, have not been characterized in\u00a0<em>Drosophila<\/em>. In this study, we find that male flies show increased ethanol hyperactivity and greater resistance to ethanol sedation compared with females. We show that the sex determination gene\u00a0<em>transformer<\/em> (tra) acts in the developing nervous system, likely through regulation of <em>fruitless<\/em> (fru).<\/em><\/p><\/blockquote>\n<p><span style=\"font-size: 13px; line-height: 19px;\">Le femmine sono pi\u00f9 morigerate, resistono meglio alla sbornia, risentono meno dei postumi. Del gene <\/span><em>fru<\/em><span style=\"font-size: 13px; line-height: 19px;\">, i soci del fan club sanno gi\u00e0 tutto. Del gene RASGRF-2 non credo anche se sembra un suo omologo.<\/span><br \/>\n<span style=\"font-size: 13px; line-height: 19px;\">Stando a un <\/span><a href=\"http:\/\/www.kcl.ac.uk\/iop\/news\/records\/2012\/December\/IMAGEN-teenage-drinking.aspx\" target=\"_blank\" rel=\"noopener\"><strong>paper<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> del <\/span><a href=\"http:\/\/www.imagen-europe.com\/\" target=\"_blank\" rel=\"noopener\"><strong>consorzio Imagen<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> &#8211; che ne avevano gi\u00e0 collegato <\/span><a href=\"http:\/\/www.pnas.org\/content\/early\/2011\/04\/05\/1017288108.abstract\" target=\"_blank\" rel=\"noopener\"><strong>un altro<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> al circuito cerebrale della ricompensa e all&#8217;abuso di alcol &#8211; i topi maschi nei quali viene soppresso sono astemi. E nel cervello di quattordicenni maschi portatori di varianti di quel gene,\u00a0l&#8217;attesa di una ricompensa (per aver risolto un compito cognitivo non legato al consumo di alcol) attiva di pi\u00f9 l&#8217;area legata alla produzione di dopamina.<\/span><br \/>\n<span style=\"font-size: 13px; line-height: 19px;\">Poi mi studio il paper, ma dubito che il RASGRF-2\u00a0sia &#8220;il gene dello sballo&#8221; che predestina all&#8217;alcolismo, come <\/span><a href=\"http:\/\/www.google.com\/webhp?source=search_app#hl=en&amp;sugexp=les%3B&amp;gs_nf=3&amp;gs_rn=0&amp;gs_ri=hp&amp;cp=23&amp;gs_id=4&amp;xhr=t&amp;q=RASGRF-2+gene+alcolismo&amp;pf=p&amp;tbo=d&amp;output=search&amp;sclient=psy-ab&amp;oq=RASGRF-2+gene+alcolismo&amp;gs_l=&amp;pbx=1&amp;bav=on.2,or.r_gc.r_pw.r_qf.&amp;fp=c5e25338c63d6017&amp;bpcl=39580677&amp;biw=1366&amp;bih=673\" target=\"_blank\" rel=\"noopener\"><strong>dicono<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\"> in <\/span><a href=\"http:\/\/www.google.com\/webhp?source=search_app#hl=en&amp;tbo=d&amp;sclient=psy-ab&amp;q=rasgrf-2+binge+drinking&amp;oq=RASGRF-2+binge+dri&amp;gs_l=hp.1.0.33i21.67769.73081.1.74982.11.11.0.0.0.0.116.870.9j2.11.0.les%3B..0.0...1c.1.evcJiDmmARA&amp;pbx=1&amp;bav=on.2,or.r_gc.r_pw.r_qf.&amp;fp=c5e25338c63d6017&amp;bpcl=39580677&amp;biw=1366&amp;bih=673\" target=\"_blank\" rel=\"noopener\"><strong>tanti<\/strong><\/a><span style=\"font-size: 13px; line-height: 19px;\">. Associato all&#8217;Auts-2, semmai conferma il dimorfismo sessuale di prima.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dall&#8217;Economist, &#8220;Text Messaging Turns Twenty&#8220;. Rif. anche il &#8220;Calendario dell&#8217;Avvento&#8221; con i grafici pi\u00f9 significativi dell&#8217;anno. Per le trattative di Doha, il Guardian mi sembra una buona fonte. La sorpresa ieri \u00e8 stata la manifestazione dell&#8217;Arab Youth Climate Movement. Per italofoni, Antonio Zecca e Luca Chiari hanno scritto per Climalteranti una versione user friendly del&hellip; <a class=\"more-link\" href=\"https:\/\/archivio.ocasapiens.org\/index.php\/2012\/12\/04\/alcolismo\/\">Continua a leggere <span class=\"screen-reader-text\">Alcolismo<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,13,17,30],"tags":[284,1427,2070,2936],"class_list":["post-14731","post","type-post","status-publish","format-standard","hentry","category-clima","category-drosophila-fanzine","category-genetica","category-tecno","tag-alcolismo","tag-clima","tag-drosophila","tag-geni","entry"],"_links":{"self":[{"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/posts\/14731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/comments?post=14731"}],"version-history":[{"count":2,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/posts\/14731\/revisions"}],"predecessor-version":[{"id":41205,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/posts\/14731\/revisions\/41205"}],"wp:attachment":[{"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/media?parent=14731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/categories?post=14731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/archivio.ocasapiens.org\/index.php\/wp-json\/wp\/v2\/tags?post=14731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}